USA dollar
  • Australian Dollar
  • British Pound Sterling

Adapalene (Differin) 0.1% Gel – Counter For Acne⼁Uses, Side Effects, and More

Adapalene (Differin) 0.1% gel plays an important role in the treatment of mild to moderate acne with comedones, papuples, and pustules. Comedones are skin bumps that grow when pores or hair follicles become clogged with germs, oil, or dead skin cells. Papules are elevated regions of skin that are less than 1 cm in diameter. Pustules are tiny skin lumps that contain pus. Acne on the face, chest, or back should be treated.

The active ingredient in the medication is adapalene, a form of topical retinoid approved by the FDA for the treatment of acne vulgaris. It contains vitamin A activity, which aids in the regulation of cell turnover, ensuring that your skin goes through the proper process. It also helps to keep skin pores free, resulting in a healthy environment for skin. .uk 3
Differin – Acne Treatment

How does Adapalene (Differin) 0.1% gel work?

The active ingredient in Differin 0.1% gel, adapalene, works by modifying cellular keratinization, decreasing microcomedone development, exfoliating mature comedones, and decreasing inflammation. It regulates some of the accumulating components that cause acne lesions within pilosebaceous units.


What does Adapalene (Differin) 0.1% gel contain?

Differin is a topical retinoid containing 0.1% adapalene that is used to treat mild to moderate acne. Adapalene was first approved by the FDA in 1996 for the treatment of mild to moderate acne in individuals aged 12 and up. Adapalene 0.1% gel has been approved by the FDA as an over-the-counter acne treatment. Other adapalene formulations, such as 0.1% lotion and cream and 0.3% gel, are only accessible by prescription.


How much is Adapalene (Differin) 0.1% gel?

Adapalene (Differin) 0.1% gel only costs $45.00 for 3 tube on Good Pharm, however other prices may vary depending on factors such as location, drugstore, and any applicable discounts or insurance coverage.


How should you take Adapalene (Differin) 0.1% gel?

Use this medicine as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than what your doctor told you as it may increase skin irritation.

Instructions for use:

Untitled design 18

  1. Apply to a clean face once daily at bedtime.

Untitled design 19

      2. The patient should wash the face with a gentle cleanser and allow the face to dry thoroughly.

Untitled design 20       3. A pea-sized amount should be applied as a thin layer to the entire face. Avoiding application to eyelids, lips and mucous membranes is necessary. Spread the medicine away from these areas when applying.

Untitled design 21       4. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

Your acne may worsen over the first three weeks of adapalene treatment. This is typical. Improvement will be visible after 4 to 8 weeks of treatment, with ongoing use predicted to result in further improvement. If your acne appears worse at first, do not discontinue using adapalene unless irritation or other symptoms become severe. Consult your doctor if your acne does not clear up within 8 to 12 weeks.

You may also feel mild skin irritation during the first two weeks of treatment, which may worsen. To reduce the risk of irritation, reduce the frequency of application to every other day, apply an oil-free moisturizer over Differin gel, or use an alternative formulation of the medicine.

It is extremely important that you continue to use this medication and complete the course of treatment even if your symptoms begin to ease up after a short period. It will aid in the prevention of new outbreaks. Differin gel will continue to clear up acne-related redness and irritation, remove blackheads and clogged pores, and restore skin texture and tone with continued use. If you discontinue this medication too soon, your acne may return or worsen.

What if you miss a dose?

What if you take too much?

If you forget to take your dose, you can do so as soon as you remember.
It and as needed, unless your next dose is approaching.
In this instance, simply skip it and resume your regular dosing schedule.
To make up for a missing dose, do not take a double dose.
Excessive use of the medicine will not result in faster or better results. It is possible to experience significant redness, peeling, or irritation.

Differin gel is only for external use. If taken accidently, it is unlikely to harm you if the amount consumed is modest. However, if you are feeling sick, consult your doctor. It may be dangerous to the baby if unintentionally consumed by pregnant women. Furthermore, continuous use of the medicine may result in the same adverse drug reactions as excessive oral vitamin A intake (e.g., headache, impaired vision, sleepiness, irritability, nausea and vomiting, abdominal pain), according to the labeling.

What are the side effects of Adapalene (Differin) 0.1% gel?

Some of the common adverse reactions of this product are usually mild and may subside on its own.

  • Photosensitivity
  • Skin irritation, redness, dryness, itching, stinging and burning sensation.


  • Exfoliation (peeling skin)
  • Sunburns if exposed to sunlight or artificial UV light
  • Contact dermatitis (local skin reactions)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your doctor.

Stop using Differin gel and contact your doctor immediately if you experience an of the following rare but serious side effects:

  • Severe allergic reactions (swelling of the face, lips, or throat)
  • Rashes, itching, hives, dizziness
  • Angioedema (painless swelling under the skin)

How should you store Adapalene (Differin) 0.1% gel?

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
  • Keep out of the reach of children.
  • Do not keep outdated medicine or medicine no longer needed.



If you want to know more about your Acne Problems just watch the video below.

YouTube video

Leave a Reply